A Prion Is Best Described as an Infectious

Hyposmia has been described as occurring early in the course of CreutzfeldtJakob disease. Inset shows domain arrangement of AIM2 inflammasome components.


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Worthy of mention is a study in knockout mice demonstrating that the physiological prion protein has a role in olfactory processing.

. C Studies have determined that mouse pro-caspase-11 mPro-caspase-11 and human pro-caspases-4 and -5 hPro-caspase-45 can directly bind intracellular. Mild olfactory dysfunction is also found in motor neuron diseases. For other prion diseases the data are insufficient.

Prion-like filaments of pro-caspase-1 violet are then able to form off of the ASC filaments inducing caspase-1 activation.


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Prion Replication Cycle Cycling Initials Generation

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